Paradoxical Effect of Trehalose on the Aggregation of α-Synuclein: Expedites Onset of Aggregation yet Reduces Fibril Load
Author:
Affiliation:
1. Department of Chemistry, Indian Institute of Technology, Delhi, Hauz-Khas, New Delhi 110016, India
Funder
Council of Scientific and Industrial Research
University Grants Commission
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00056
Reference128 articles.
1. Protein aggregation and neurodegenerative disease
2. Peptide Aggregation in Neurodegenerative Disease
3. Amyloid fibrils
4. Amyloid deposits: Protection against toxic protein species?
5. THE BIOCHEMISTRY OF PARKINSON'S DISEASE
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