Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity-Reference-Cited by-同舟云学术

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Dual 5-HT6 and D3 Receptor Antagonists in a Group of 1H-Pyrrolo[3,2-c]quinolines with Neuroprotective and Procognitive Activity

Published:2019-03-21 Issue:7 Volume:10 Page:3183-3196
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Grychowska Katarzyna,Chaumont-Dubel Severine¹,Kurczab Rafał^ORCID,Koczurkiewicz Paulina,Deville Caroline,Krawczyk Martyna,Pietruś Wojciech,Satała Grzegorz,Buda Szymon²,Piska Kamil,Drop Marcin,Bantreil Xavier³^ORCID,Lamaty Frédéric³^ORCID,Pękala Elżbieta,Bojarski Andrzej J.^ORCID,Popik Piotr,Marin Philippe¹,Zajdel Paweł^ORCID

Affiliation:

1. IGF, Université de Montpellier, CNRS INSERM, 34094 Montpellier, France

2. Faculty of Chemistry, Jagiellonian University, 2 Gronostajowa Str., 30-387 Kraków, Poland

3. IBMM, UMR 5247, CNRS, Université de Montpellier, ENSCM, Place Eugène Bataillon, 34095 Montpellier, France

Funder

Agence Nationale de la Recherche

Institut National de la Sant? et de la Recherche M?dicale

Uniwersytet Jagiellonski Collegium Medicum

Universit? de Montpellier

Narodowe Centrum Nauki

Fondation pour la Recherche M?dicale

Centre National de la Recherche Scientifique

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00618

Reference59 articles.

1. Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

2. Shifting from the single to the multitarget paradigm in drug discovery

3. Altering the course of schizophrenia: progress and perspectives

4. Antagonism of the 5-HT 6 receptor – Preclinical rationale for the treatment of Alzheimer's disease

5. Novel non-sulfonamide 5-HT 6 receptor partial inverse agonist in a group of imidazo[4,5- b ]pyridines with cognition enhancing properties

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1. 5-HT6 receptor neutral antagonists protect astrocytes: A lesson from 2-phenylpyrrole derivatives;European Journal of Medicinal Chemistry;2024-09

2. Biological properties of pyrroloquinoline and pyrroloisoquinoline derivatives;European Journal of Medicinal Chemistry;2024-04

3. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT₆ Agents with a Beneficial Neuroprotective Profile against Alzheimer’s Disease;Journal of Medicinal Chemistry;2024-01-08

4. Enal-azomethine ylides: application in the synthesis of functionalized pyrroles;Organic & Biomolecular Chemistry;2024

5. Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT6 and D3R Affinity in the 1H-Pyrrolo[3,2-c]quinoline Series;Molecules;2023-01-21

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