Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules-Reference-Cited by-同舟云学术

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules

Published:2018-05-11 Issue:11 Volume:9 Page:2521-2527
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Hsieh Chia-Ju¹^ORCID,Ferrie John J.²,Xu Kuiying¹,Lee Iljung¹,Graham Thomas J. A.¹,Tu Zhude³^ORCID,Yu Jennifer⁴,Dhavale Dhruva⁴,Kotzbauer Paul⁴,Petersson E. James²,Mach Robert H.¹^ORCID

Affiliation:

1. Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

3. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States

4. Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, United States

Funder

National Institute of Neurological Disorders and Stroke

Division of Graduate Education

Michael J. Fox Foundation for Parkinson's Research

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00177

Reference33 articles.

1. Synucleins in synaptic plasticity and neurodegenerative disorders

2. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

3. C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction

4. The fold of -synuclein fibrils

5. -Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies

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