A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450BM3-Reference-Cited by-同舟云学术

A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450BM3

Published:2009-03-20 Issue:4 Volume:4 Page:261-267
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Dietrich Jeffrey A.¹²,Yoshikuni Yasuo¹²³⁴,Fisher Karl J.⁵,Woolard Frank X.⁵,Ockey Denise⁵,McPhee Derek J.⁵,Renninger Neil S.⁵,Chang Michelle C. Y.⁶⁷²,Baker David³⁴,Keasling Jay D.¹⁶⁸²⁹

Affiliation:

1. UCSF/UCB Joint Graduate Group in Bioengineering

2. Synthetic Biology Department, Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94710

3. Department of Biochemistry, University of Washington, Seattle, Washington 98195

4. Howard Hughes Medical Institute, Seattle, Washington 98195

5. Amyris Biotechnologies Inc., Emeryville, California 94208

6. California Institute for Quantitative Biomedical Research (QB3)

7. Department of Chemistry

8. Department of Chemical Engineering, University of California at Berkeley, Berkeley, California 94720

9. Joint BioEnergy Institute, Emeryville, California 94208

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb900006h

Reference36 articles.

1. ENZYME RECRUITMENT IN EVOLUTION OF NEW FUNCTION

2. Enzyme promiscuity: mechanism and applications

3. Microbially Derived Artemisinin: A Biotechnology Solution to the Global Problem of Access to Affordable Antimalarial Drugs

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