1. Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba 260-8673, Japan, Research Laboratory, Higeta Shoyu Co., Ltd., Chiba 288-8680, Japan, Cancer Research Institute, Kanazawa University, Kanazawa 920-0934, Japan, and Osaka University of Pharmaceutical Sciences, Takatsuki 569-1094, Japan