Differential Binding of RhoA, RhoB, and RhoC to Protein Kinase C-Related Kinase (PRK) Isoforms PRK1, PRK2, and PRK3: PRKs Have the Highest Affinity for RhoB-Reference-Cited by-同舟云学术

Differential Binding of RhoA, RhoB, and RhoC to Protein Kinase C-Related Kinase (PRK) Isoforms PRK1, PRK2, and PRK3: PRKs Have the Highest Affinity for RhoB

Published:2013-10-31 Issue:45 Volume:52 Page:7999-8011
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Hutchinson Catherine L.¹,Lowe Peter N.²,McLaughlin Stephen H.¹³,Mott Helen R.¹,Owen Darerca¹

Affiliation:

1. Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, U.K.

2. Biomolecular Interactions Consultancy, 3 Danesbury Park, Hertford SG14 3HX, U.K.

3. MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, U.K.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi401216w

Reference54 articles.

1. The role of the Rho GTPases in neuronal development

2. ROCK, PAK, and Toll of synapses in Alzheimer’s disease

3. Rho kinase, a promising drug target for neurological disorders

4. Targeting Rho and Rho-kinase in the treatment of cardiovascular disease

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