“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates-Reference-Cited by-同舟云学术

“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates

Published:2017-12-21 Issue:1 Volume:140 Page:200-210
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Mortenson David E.¹,Brighty Gabriel J.¹,Plate Lars¹,Bare Grant¹,Chen Wentao¹,Li Suhua¹^ORCID,Wang Hua¹^ORCID,Cravatt Benjamin F.¹^ORCID,Forli Stefano¹^ORCID,Powers Evan T.¹,Sharpless K. Barry¹,Wilson Ian A.¹,Kelly Jeffery W.¹^ORCID

Affiliation:

1. Department of Molecular Medicine, ‡Department of Chemistry, §Department of Integrative, Structural and Computational Biology, and ∥The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California 92037, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Leukemia and Lymphoma Society

National Institute of General Medical Sciences

Hewitt Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.7b08366

Reference70 articles.