12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents-Reference-Cited by-同舟云学术

12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents

Published:2017-05-17 Issue:21 Volume:139 Page:7318-7334
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Nicolaou K. C.¹^ORCID,Rhoades Derek¹^ORCID,Wang Yanping¹,Bai Ruoli²,Hamel Ernest²,Aujay Monette³,Sandoval Joseph³,Gavrilyuk Julia³

Affiliation:

1. Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, Texas 77005, United States

2. Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, United States

3. Abbvie Stemcentrx, LLC, 450 East Jamie Court, South San Francisco, California 94080, United States

Funder

Cancer Prevention and Research Institute of Texas

National Institutes of Health

The Welch Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.7b02655

Reference91 articles.