Semisynthesis, Biological Activity, and Molecular Modeling Studies of C-Ring-Modified Camptothecins-Reference-Cited by-同舟云学术

Semisynthesis, Biological Activity, and Molecular Modeling Studies of C-Ring-Modified Camptothecins

Published:2009-02-03 Issue:4 Volume:52 Page:1029-1039
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Samorì Cristian¹,Guerrini Andrea¹,Varchi Greta¹,Fontana Gabriele¹,Bombardelli Ezio¹,Tinelli Stella¹,Beretta Giovanni Luca¹,Basili Serena¹,Moro Stefano¹,Zunino Franco¹,Battaglia Arturo¹

Affiliation:

1. Istituto CNR per la Sintesi Organica e Fotoreattività “I.S.O.F.”, Area della Ricerca di Bologna, Via P. Gobetti 101, 40129 Bologna, Italy, Indena SPA, Viale Ortles 12, 20139 Milano, Italy, Diparitmento di Oncologia Sperimentale e Laboratori, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milano, Italy, and Molecular Modelling Section (MMS), Dipartimento di Scienze Farmaceutiche, Università di Padova, Via Marzolo 5, I-35131 Padova, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801153y

Reference63 articles.

1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

2. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

3. In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems

4. CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer.

5. Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

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