10-(2-oxo-2-Phenylethylidene)-10H-anthracen-9-ones as Highly Active Antimicrotubule Agents: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization-Reference-Cited by-同舟云学术

10-(2-oxo-2-Phenylethylidene)-10H-anthracen-9-ones as Highly Active Antimicrotubule Agents: Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization

Published:2009-02-16 Issue:5 Volume:52 Page:1284-1294
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Prinz Helge¹,Schmidt Peter¹,Böhm Konrad J.¹,Baasner Silke¹,Müller Klaus¹,Unger Eberhard¹,Gerlach Matthias¹,Günther Eckhard G.¹

Affiliation:

1. Institute of Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms-University, Hittorfstrasse 58-62, D-48149 Münster, Germany, Leibniz Institute for Age Research—Fritz Lipmann Institute (FLI), Beutenbergstrasse 11, D-07745 Jena, Germany, ÆternaZentaris GmbH, Weismüllerstrasse 50, D-60314 Frankfurt, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801338r

Reference46 articles.

1. Understanding microtubule dynamics for improved cancer therapy

2. Review: Tubulin Function, Action of Antitubulin Drugs, and New Drug Development

3. Mechanism of Action of Antitumor Drugs that Interact with Microtubules and Tubulin

4. Discovery and development of antimitotic agents that inhibit tubulin polymerisation for the treatment of cancer

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