Identification of Potential Genomic Biomarkers of Hepatotoxicity Caused by Reactive Metabolites of N-Methylformamide: Application of Stable Isotope Labeled Compounds in Toxicogenomic Studies-Reference-Cited by-同舟云学术

Identification of Potential Genomic Biomarkers of Hepatotoxicity Caused by Reactive Metabolites of N-Methylformamide: Application of Stable Isotope Labeled Compounds in Toxicogenomic Studies

Published:2006-09-08 Issue:10 Volume:19 Page:1270-1283
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Mutlib Abdul¹,Jiang Ping¹,Atherton Jim¹,Obert Leslie¹,Kostrubsky Seva¹,Madore Steven¹,Nelson Sidney¹

Affiliation:

1. Departments of Pharmacokinetics, Dynamics and Metabolism, Discovery Biomarkers Group and Safety Sciences, Pfizer Global Research and Development, Michigan Laboratories, 2800 Plymouth Road, Ann Arbor, Michigan 48105 Department of Medicinal Chemistry, School of Pharmacy, University of Washington, H364C Health Sciences Center, P.O. Box 357631, Seattle, Washington 98195-7631

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx060093j

Reference42 articles.

1. Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development

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