Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development-Reference-Cited by-同舟云学术

Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development

Published:2003-12-12 Issue:1 Volume:17 Page:3-16
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Evans David C.¹,Watt Alan P.¹,Nicoll-Griffith Deborah A.¹,Baillie Thomas A.¹

Affiliation:

1. Drug Metabolism, Merck & Co., Inc., Rahway, New Jersey, Medicinal Chemistry, Drug Metabolism Section, Merck Sharp & Dohme, Terlings Park, United Kingdom, Medicinal Chemistry, Merck Frosst Center for Therapeutic Research, Kirkland, Quebec, Canada, and Drug Metabolism, Merck & Co., Inc., West Point, Pennsylvania

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx034170b

Reference106 articles.

1. Carcinogenic Activity, Structure, and Chemical Reactivity of Polynuclear Aromatic Hydrocarbons

2. Biochemical Mechanisms of Drug Toxicity

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