Synthesis and Modeling of New Benzofuranone Histone Deacetylase Inhibitors that Stimulate Tumor Suppressor Gene Expression-Reference-Cited by-同舟云学术

Synthesis and Modeling of New Benzofuranone Histone Deacetylase Inhibitors that Stimulate Tumor Suppressor Gene Expression

Published:2009-04-22 Issue:9 Volume:52 Page:3112-3115
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Charrier Cédric¹,Clarhaut Jonathan¹,Gesson Jean-Pierre¹,Estiu Guillermina¹,Wiest Olaf¹,Roche Joëlle¹,Bertrand Philippe¹

Affiliation:

1. Laboratoire Synthèse et Réactivité des Substances Naturelles, Université de Poitiers, CNRS-UMR 6514, 40 Avenue du Recteur Pineau, Poitiers F-86022, France, Institut de Physiologie et de Biologie Cellulaires, Université de Poitiers, CNRS-UMR 6187, 40 Avenue du Recteur Pineau, Poitiers F-86022, France, Walther Cancer Research Center, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556-5670

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9002439

Reference19 articles.

1. Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

2. Histone deacetylase inhibitors: molecular mechanisms of action

3. Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design

4. Histone Deacetylase Inhibitors: Overview and Perspectives

5. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

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