Synthesis of (E)-2-(1-(methoxyimino)ethyl)-2-phenylbenzofuran-3(2H)-ones from (E)-1-(benzofuran-2-yl)ethan-1-one O-methyl oximes and iodobenzenes via a palladium-catalyzed dearomative arylation/oxidation reaction-Reference-Cited by-同舟云学术

Synthesis of (E)-2-(1-(methoxyimino)ethyl)-2-phenylbenzofuran-3(2H)-ones from (E)-1-(benzofuran-2-yl)ethan-1-one O-methyl oximes and iodobenzenes via a palladium-catalyzed dearomative arylation/oxidation reaction

Published:2023 Issue:31 Volume:21 Page:6307-6311
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhu Wen-Jing¹,Yu Xiao¹,Liu Hong-Yan¹,Liu Yi¹,Zhao Jin-Bo¹,Zhang Peng-Fei²^ORCID,Xia Cheng-Cai¹^ORCID,Li Fu-Rong¹

Affiliation:

1. School of Pharmacy College, Institute of Pharmacology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China

2. College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou, 311121, China

Abstract

A novel route for a tandem addition and oxidation reaction featuring mild reaction conditions and good functional group tolerance has been developed, providing a direct approach for the preparation of 2,2-disubstituted benzofuran-3(2H)-ones.

Funder

Shandong First Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00772C

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