Crystal Structure of the Hydrated Strontium Salt of Methotrexate: Two Independent Molecules with Different Conformations
Author:
Affiliation:
1. ARDONO Research, 8515-C 35th Avenue NE, Seattle, Washington 98115, and Biochemistry Department, University of Toronto, Toronto M5S 1A8, Canada
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm000114l
Reference14 articles.
1. Absolute configuration of biological tetrahydrofolates. A crystallographic determination
2. Folic Acid: Crystal Structure and Implications for Enzyme Binding
3. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
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