Structural characteristics of small-molecule antifolate compounds
Author:
Publisher
Informa UK Limited
Subject
Condensed Matter Physics,General Materials Science,Biochemistry,General Chemistry,Structural Biology
Link
http://www.tandfonline.com/doi/pdf/10.1080/08893110701337800
Reference216 articles.
1. Blakely, RL. 1995.Advances in Enzymology & Related Areas of Molecular Biology, Vol. 70, 23–102. New York: John Wiley & Sons.
2. New insights into DHFR interactions: Analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(ω-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stack
3. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs
4. Conformational changes of small molecules binding to proteins
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. The characteristic structural and functional dynamics of P. falciparum DHFR binding with pyrimidine chemotypes implicate malaria therapy design;Chemical Physics Impact;2024-12
2. The Characteristic Structural and Functional Dynamics of P. Falciparum Dhfr Binding with Pyrimidine Chemotypes Implicate Malaria Therapy Design;2024
3. Vibrational Spectroscopic Investigations, Electronic Properties, Molecular Structure and Quantum Mechanical Study of an Antifolate Drug: Pyrimethamine;Computational Chemistry;2022
4. One barbiturate and two solvated thiobarbiturates containing the triply hydrogen-bondedADA/DADsynthon, plus one ansolvate and three solvates of their coformer 2,4-diaminopyrimidine;Acta Crystallographica Section C Structural Chemistry;2016-08-26
5. Modified 2,4-diaminopyrimidine-based dihydrofolate reductase inhibitors as potential drug scaffolds against Bacillus anthracis;Bioorganic & Medicinal Chemistry;2015-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3