Discovery of a New Class of Anilinoquinazoline Inhibitors with High Affinity and Specificity for the Tyrosine Kinase Domain of c-Src-Reference-Cited by-同舟云学术

Discovery of a New Class of Anilinoquinazoline Inhibitors with High Affinity and Specificity for the Tyrosine Kinase Domain of c-Src

Published:2004-01-14 Issue:4 Volume:47 Page:871-887
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Plé Patrick A.¹,Green Tim P.¹,Hennequin Laurent F.¹,Curwen Jon¹,Fennell Michael¹,Allen Jack¹,Lambert-van der Brempt Christine¹,Costello Gerard¹

Affiliation:

1. AstraZeneca, Centre de Recherches, Z.I.S.E. La Pompelle B.P.1050, 51689 Reims Cedex 2, France, and AstraZeneca Pharmaceuticals, Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030317k

Reference58 articles.

1. Identification of a transformation-specific antigen induced by an avian sarcoma virus

2. Identification of a polypeptide encoded by the avian sarcoma virus src gene.

3. Protein kinase activity associated with the avian sarcoma virus src gene product.

4. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

5. Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

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