Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease-Reference-Cited by-同舟云学术

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Published:2010-08-20 Issue:18 Volume:53 Page:6653-6680
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Becker Daniel P.¹,Barta Thomas E.¹,Bedell Louis J.¹,Boehm Terri L.¹,Bond Brian R.¹,Carroll Jeffery¹,Carron Chris P.¹,DeCrescenzo Gary A.¹,Easton Alan M.¹,Freskos John N.¹,Funckes-Shippy Chris L.¹,Heron Marcia¹,Hockerman Susan¹,Howard Carol Pearcy¹,Kiefer James R.¹,Li Madeleine H.¹,Mathis Karl J.¹,McDonald Joseph J.¹,Mehta Pramod P.¹,Munie Grace E.¹,Sunyer Teresa¹,Swearingen Craig A.¹,Villamil Clara I.¹,Welsch Dean¹,Williams Jennifer M.¹,Yu Ying¹,Yao Jun¹

Affiliation:

1. Pfizer Research, 700 Chesterfield Village Parkway, St. Louis, Missouri 63198

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100669j

Reference75 articles.

1. Matrix Metalloproteinases

2. Matrix metalloproteinases: a tail of a frog that became a prince

3. COLLAGENOLYTIC ACTIVITY IN AMPHIBIAN TISSUES: A TISSUE CULTURE ASSAY