Xanthine Derivative KMUP-1 Reduces Inflammation and Hyperalgesia in a Bilateral Chronic Constriction Injury Model by Suppressing MAPK and NFκB Activation

Author:

Dai Zen-Kong1,Lin Ting-Chun2,Liou Jau-Cheng3,Cheng Kuang-I4,Chen Jun-Yih5,Chu Li-Wen6,Chen Ing-Jun2,Wu Bin-Nan2

Affiliation:

1. Department of Pediatrics, Division of Pediatric Pulmonology and Cardiology, Kaohsiung Medical University Hospital, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

2. Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

3. Department of Biological Sciences, National Sun Yat-Sen University, No. 70, Lianhai Road, Kaohsiung, Taiwan

4. Department of Anesthesiology, School of Medicine, College of Medicine, Kaohsiung Medical University and Hospital, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

5. Department of Neurosurgery, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1st Road, Kaohsiung, Taiwan

6. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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