Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors-Reference-Cited by-同舟云学术

Discovery and Evaluation of Potent P1 Aryl Heterocycle-Based Thrombin Inhibitors

Published:2004-05-08 Issue:12 Volume:47 Page:2995-3008
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Young Mary Beth¹,Barrow James C.¹,Glass Kristen L.¹,Lundell George F.¹,Newton Christina L.¹,Pellicore Janetta M.¹,Rittle Kenneth E.¹,Selnick Harold G.¹,Stauffer Kenneth J.¹,Vacca Joseph P.¹,Williams Peter D.¹,Bohn Dennis¹,Clayton Franklin C.¹,Cook Jacquelynn J.¹,Krueger Julie A.¹,Kuo Lawrence C.¹,Lewis S. Dale¹,Lucas Bobby J.¹,McMasters Daniel R.¹,Miller-Stein Cynthia¹,Pietrak Beth L.¹,Wallace Audrey A.¹,White Rebecca B.¹,Wong Bradley¹,Yan Youwei¹,Nantermet Philippe G.¹

Affiliation:

1. Medicinal Chemistry, Pharmacology, Biological Chemistry, Structural Biology, Molecular Systems, and Drug Metabolism, Merck Research Laboratories, Merck and Co., Inc., WP14-3, Post Office Box 4, Sumneytown Pike, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030303e

Reference22 articles.

1. Pharmacology; Brenner, G. M.; W. B. Saunders Co. Philadelphia, 2000.

2. Melagatran and Ximelagatran

3. Thrombolytic therapy: 2001

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