Stereostructure and Biological Activity of 42-Hydroxy-palytoxin: A New Palytoxin Analogue from Hawaiian Palythoa Subspecies

Author:

Ciminiello Patrizia1,Dell’Aversano Carmela1,Dello Iacovo Emma1,Fattorusso Ernesto1,Forino Martino1,Grauso Laura1,Tartaglione Luciana1,Florio Chiara1,Lorenzon Paola1,De Bortoli Marco1,Tubaro Aurelia1,Poli Mark1,Bignami Gary1

Affiliation:

1. Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli “Federico II”, via D. Montesano, 49, 80131 Napoli, Italy, Department of Life Sciences, Università degli Studi di Trieste, Via Fleming 22, and DMRN, Università degli Studi di Trieste, Via Valerio 6, 34127 Trieste, Italy, Integrated Toxicology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702-5011, and PanThera Biopharma, 99-193 Aiea Heights Drive, Suite 136, Aiea, Hawaii 96701

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Reference44 articles.

1. Malo, D. (1951) Hawaiian Antiquities,2nd ed., pp201−226,B. P. Bishop Museum Special Publication 2,Honolulu.

2. Palytoxin: A New Marine Toxin from a Coelenterate

3. A review of Hawaiian zoanthids with descriptions of three new species

4. Toxicological evaluation of palytoxin in several animal species

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