Strategy and Its Implications of Protein Bioanalysis Utilizing High-Resolution Mass Spectrometric Detection of Intact Protein-Reference-Cited by-同舟云学术

Strategy and Its Implications of Protein Bioanalysis Utilizing High-Resolution Mass Spectrometric Detection of Intact Protein

Published:2011-11-01 Issue:23 Volume:83 Page:8937-8944
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Ruan Qian¹,Ji Qin C.¹,Arnold Mark E.¹,Humphreys W. Griffith¹,Zhu Mingshe¹

Affiliation:

1. Biotransformation and ‡Bioanalytical Sciences, Bristol-Myers Squibb Comapny, Route 206 and Province Line Road, Princeton, New Jersey 08543, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac201540t

Reference18 articles.

1. Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies

2. Protein Quantitation through Targeted Mass Spectrometry: The Way Out of Biomarker Purgatory?

3. Towards Absolute Quantification of Therapeutic Monoclonal Antibody in Serum by LC−MS/MS Using Isotope-Labeled Antibody Standard and Protein Cleavage Isotope Dilution Mass Spectrometry

4. A Universal Strategy for Development of a Method for Absolute Quantification of Therapeutic Monoclonal Antibodies in Biological Matrices Using Differential Dimethyl Labeling Coupled with Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry

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