Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of Bridged and Fused Ring Analogues of Epibatidine
Author:
Affiliation:
1. Organic and Medicinal Chemistry, Research Triangle Institute, Research Triangle Park, North Carolina 27709, and Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia 23298
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0704696
Reference38 articles.
1. Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog
2. Antinociceptive effects of the alkaloid epibatidine: Further studies on involvement of nicotinic receptors
3. Pharmacological effects of epibatidine optical enantiomers
4. Epibatidine structure–activity relationships
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