Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection-Reference-Cited by-同舟云学术

Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection

Published:2012-06-05 Issue:12 Volume:84 Page:5380-5386
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Michels David A.¹,Tu Andrea W.²,McElroy Will¹,Voehringer David²,Salas-Solano Oscar³

Affiliation:

1. Department of Protein Analytical Chemistry, Genentech, a Member of the Roche Group, 1 DNA Way, South San Francisco, California 94080, United States

2. ProteinSimple, 3040 Oakmead Village Drive, Santa Clara, California 95051, United States

3. Department of Analytical Biochemistry, Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington 98021, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac3008847

Reference21 articles.

1. Charge variants in IgG1

2. Recent developments in capillary isoelectric focusing with whole-column imaging detection

3. Recent advances in capillary isoelectric focusing: 1997–2001

4. Characterization of Antibody Charge Heterogeneity Resolved by Preparative Immobilized pH Gradients

5. Identification of isomerization and racemization of aspartate in the Asp–Asp motifs of a therapeutic protein

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