Identification of isomerization and racemization of aspartate in the Asp–Asp motifs of a therapeutic protein

Author:

Zhang Jennifer,Yip Holly,Katta Viswanatham

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference57 articles.

1. Co-operative effects of functional groups in peptides. I. Aspartyl-serine derivatives;Bernhard;J. Am. Chem. Soc.,1962

2. Stability of Protein Pharmaceuticals Part A: Chemical and Physical Pathways of Protein Degradation;Clarke,1992

3. Formulation Characterization, and Stability of Protein Drugs;Powell,1996

4. Deamidation and racemization at asparaginyl and aspartyl residues in peptides;Geiger;J. Biol. Chem.,1987

5. Chemical pathways of peptide degradation III: effect of primary sequence on the pathways on deamidation of asparaginyl residues in hexapeptides;Patel;Pharm. Res.,1990

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