Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion-Reference-Cited by-同舟云学术

Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion

Published:2022-12-13 Issue:12 Volume:16 Page:20163-20173
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Aliakbarinodehi Nima¹^ORCID,Gallud Audrey²³^ORCID,Mapar Mokhtar¹^ORCID,Wesén Emelie²^ORCID,Heydari Sahar²^ORCID,Jing Yujia³^ORCID,Emilsson Gustav³^ORCID,Liu Kai³^ORCID,Sabirsh Alan³^ORCID,Zhdanov Vladimir P.¹⁴^ORCID,Lindfors Lennart³^ORCID,Esbjörner Elin K.²^ORCID,Höök Fredrik¹^ORCID

Affiliation:

1. Division of Nano and Biophysics, Department of Physics, Chalmers University of Technology 41296 Göteborg, Sweden

2. Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Göteborg, Sweden

3. Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden

4. Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk 630090, Russia

Funder

Stiftelsen f?r Strategisk Forskning

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.2c04829

Reference66 articles.

1. Lipid nanoparticles for mRNA delivery

2. Delivery of Oligonucleotide Therapeutics: Chemical Modifications, Lipid Nanoparticles, and Extracellular Vesicles

3. Molecular assemblies and membrane domains in multivesicular endosome dynamics

4. Carriers Break Barriers in Drug Delivery: Endocytosis and Endosomal Escape of Gene Delivery Vectors

5. Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

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