Delivery of Oligonucleotide Therapeutics: Chemical Modifications, Lipid Nanoparticles, and Extracellular Vesicles

Author:

Bost Jeremy P.1ORCID,Barriga Hanna2,Holme Margaret N.2ORCID,Gallud Audrey34ORCID,Maugeri Marco5,Gupta Dhanu1,Lehto Taavi16,Valadi Hadi5,Esbjörner Elin K.3ORCID,Stevens Molly M.27ORCID,El-Andaloussi Samir1

Affiliation:

1. Department of Laboratory Medicine, Karolinska Institutet, Huddinge 14152, Sweden

2. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden

3. Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg 41296, Sweden

4. Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg 43150, Sweden

5. Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 41390, Sweden

6. Institute of Technology, University of Tartu, Nooruse 1, Tartu 50411, Estonia

7. Department of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, London SW7 2BU, United Kingdom

Funder

AstraZeneca

Royal Academy of Engineering

Stiftelsen f??r??Strategisk Forskning

UK Regenerative Medicine Platform

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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