Intravenous Delivery of Living Listeria monocytogenes Elicits Gasdmermin-Dependent Tumor Pyroptosis and Motivates Anti-Tumor Immune Response

Author:

Liu Yao12,Lu Yiping3,Ning Bo4,Su Xiaomin4,Yang Binru5,Dong Haiqing1ORCID,Yin Bo3,Pang Zhiqing6ORCID,Shen Shun2ORCID

Affiliation:

1. Key Laboratory of Spine and Spinal Cord Injury Repair, and Regeneration of Ministry of Education, Orthopaedic Department of Tongji Hospital. The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai 200092, P. R. China

2. Pharmacy Department & Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai 201399, China

3. Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China

4. Central laboratory, First Affiliated Hospital, Institute (college) of Integrative Medicine, Dalian Medical University, Dalian 116021, China

5. State Key Laboratory of Molecular Engineering of Polymers & Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China

6. School of Pharmacy & Key Laboratory of Smart Drug Delivery, Fudan University, Shanghai 201203, China

Funder

Shanghai Municipal Health and Family Planning Commission

National Natural Science Foundation of China

Shanghai Pudong Hospital

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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