Bridging Converts a Noncytotoxic nor-Paclitaxel Derivative to a Cytotoxic Analogue by Constraining It to the T-Taxol Conformation-Reference-Cited by-同舟云学术

Bridging Converts a Noncytotoxic nor-Paclitaxel Derivative to a Cytotoxic Analogue by Constraining It to the T-Taxol Conformation

Published:2006-08-01 Issue:18 Volume:8 Page:3983-3986
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Tang Shoubin¹,Yang Chao¹,Brodie Peggy¹,Bane Susan¹,Ravindra Rudravajhala¹,Sharma Shubhada¹,Jiang Yi¹,Snyder James P.¹,Kingston David G. I.¹

Affiliation:

1. Department of Chemistry, M/C 0212, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, Department of Chemistry, State University of New York at Binghamton, Binghamton, New York 13902, and Department of Chemistry, Emory University, Atlanta, Georgia 30322

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol061438s

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2. (a) Kingston, D. G. I. 2005 InAnticancer Agents from NaturalProducts; Cragg, G. M., Kingston, D. G. I., Newman, D. J. Eds.; CRC Press: Boca Raton, 2005; pp 89−122.

3. Promotion of microtubule assembly in vitro by taxol

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