Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-κB Activation-Reference-Cited by-同舟云学术

Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-κB Activation

Published:2013-05-31 Issue:11 Volume:56 Page:4749-4757
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Yu¹²,Su Jia¹³,Goto Masuo²,Morris-Natschke Susan L.²,Li Yan¹,Zhao Qin-Shi¹,Yao Zhu-Jun⁴,Lee Kuo-Hsiung²⁵⁶

Affiliation:

1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China

2. Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7568, United States

3. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

4. State Key Laboratory of Bioorganic and Natural Products Chemistry, EISU Chemical Biology Division, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

5. UNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, 27599-7295, United States United States

6. Chinese Medicine Research and Development Center, China Medical University and Hospital, 2 Yuh-Der Road, Taichung 40447, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400479p

Reference27 articles.

1. Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?

2. Natural products in cancer chemotherapy: past, present and future

3. From Single- to Multi-Target Drugs in Cancer Therapy: When Aspecificity Becomes an Advantage