Antitumor Agents. 163. Three-Dimensional Quantitative Structure−Activity Relationship Study of 4‘-O-Demethylepipodophyllotoxin Analogs Using the Modified CoMFA/q2-GRS Approach-Reference-Cited by-同舟云学术

Antitumor Agents. 163. Three-Dimensional Quantitative Structure−Activity Relationship Study of 4‘-O-Demethylepipodophyllotoxin Analogs Using the Modified CoMFA/q2-GRS Approach

Published:1996-01-01 Issue:7 Volume:39 Page:1383-1395
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cho Sung Jin¹,Tropsha Alexander¹,Suffness Matthew¹,Cheng Yung-Chi¹,Lee Kuo-Hsiung¹

Affiliation:

1. Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, Division of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20892, and Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9503052

Reference33 articles.

1. Antitumor Agents, 162. Cell-Based Assays for Identifying Novel DNA Topoisomerase Inhibitors: Studies on the Constituents of Fatsia japonica

2. Pharmakologische Studien über Podophyllum peltatum

3. Jardin, I. Podophyllotoxins. InAnticancer Agents Based on Natural Product Models; Cassady, J. M., Douros, J. D., Eds.; Academic Press: New York, 1980; pp 319−351.

4. Podophyllotoxin, steganacin and combretastatin: Natural products that bind at the colchicine site of tubulin

Cited by 94 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Organo NHC catalyzed aqueous synthesis of 4β-isoxazole-podophyllotoxins: in vitro anticancer, caspase activation, tubulin polymerization inhibition and molecular docking studies;RSC Advances;2024

3. Lead/Drug Discovery from Natural Resources;Molecules;2022-11-28

4. Synthesis and cytotoxicity of new 4-aza-2,3-didehydropodophyllotoxins;Vietnam Journal of Science and Technology;2022-03-23

5. Podophyllotoxin: History, Recent Advances and Future Prospects;Biomolecules;2021-04-19