1. Department of Pharmaceutical Chemistry, University of Kansas, Lawrence Kansas 66047, Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87115, Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, Kansas 66047, and Department of Pharmacy Practice, College of Pharmacy, University of New Mexico Health Sciences Center