Advances and opportunities in nanoimaging agents for the diagnosis of inflammatory lung diseases

Author:

Masanam Hema Brindha1ORCID,Perumal Govindaraj23,Krishnan Saravanan4,Singh Sachin Kumar5,Jha Niraj Kumar6ORCID,Chellappan Dinesh Kumar7ORCID,Dua Kamal8ORCID,Gupta Piyush Kumar91011ORCID,Narasimhan Ashwin Kumar1ORCID

Affiliation:

1. Advanced Nano-Theranostics (ANTs), Biomaterials Lab, Department of Biomedical Engineering, SRM Institute of Science & Technology, Kattankulathur, Tamil Nadu, 603 203, India

2. Department of Conservative Dentistry & Endodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Velappanchavadi, Chennai, 600 077, India

3. Department of Biomedical Engineering, Rajalakshmi Engineering College, Thandalam, Chennai, 602 105, India

4. Creative Carbon Labs Pvt Ltd, Chennai, Tamil Nadu, 600113, India

5. School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India

6. Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Knowledge Park III, Greater Noida, Uttar Pradesh, 201310, India

7. Department of Life Sciences, School of Pharmacy, International Medical University (IMU), Bukit Jalil, Kuala Lumpur, 57000, Malaysia

8. Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia

9. Department of Life Sciences, School of Basic Sciences & Research (SBSR), Sharda University, Knowledge Park III, Greater Noida, Uttar Pradesh, 201310, India

10. Department of Biotechnology, Graphic Era Deemed to be University, Dehradun, Uttarakhand, 248002, India

11. Faculty of Health and Life Sciences, INTI International University, Nilai 71800, Malaysia

Abstract

The development of rapid, noninvasive diagnostics to detect lung diseases is a great need after the COVID-2019 outbreak. The nanotechnology-based approach has improved imaging and facilitates the early diagnosis of inflammatory lung diseases. The multifunctional properties of nanoprobes enable better spatial–temporal resolution and a high signal-to-noise ratio in imaging. Targeted nanoimaging agents have been used to bind specific tissues in inflammatory lungs for early-stage diagnosis. However, nanobased imaging approaches for inflammatory lung diseases are still in their infancy. This review provides a solution-focused approach to exploring medical imaging technologies and nanoprobes for the detection of inflammatory lung diseases. Prospects for the development of contrast agents for lung disease detection are also discussed.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

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