Rapid Identification of a Novel Small Molecule Phosphodiesterase 10A (PDE10A) Tracer-Reference-Cited by-同舟云学术

Rapid Identification of a Novel Small Molecule Phosphodiesterase 10A (PDE10A) Tracer

Published:2012-05-11 Issue:10 Volume:55 Page:4776-4787
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hu Essa¹²,Ma Ji¹²,Biorn Christopher¹²,Lester-Zeiner Dianna¹²,Cho Robert¹²,Rumfelt Shannon¹²,Kunz Roxanne K.¹²,Nixey Thomas¹²,Michelsen Klaus¹²,Miller Silke¹²,Shi Jianxia¹²,Wong Jamie¹²,Hill Della Puppa Geraldine¹²,Able Jessica¹²,Talreja Santosh¹²,Hwang Dah-Ren¹²,Hitchcock Stephen A.¹²,Porter Amy¹²,Immke David¹²,Allen Jennifer R.¹²,Treanor James¹²,Chen Hang¹²

Affiliation:

1. Department of Small Molecule Chemistry, ‡Department of Neuroscience, §Department of Molecular Structures, and ∥Department of Medical Sciences, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States

2. Department of Neuroscience and #Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3002372

Reference40 articles.

1. Using positron emission tomography to facilitate CNS drug development

2. The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development

3. The Role of Molecular Imaging in Drug Discovery and Development

4. Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

5. Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling

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