Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues-Reference-Cited by-同舟云学术

Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues

Published:1998-12-01 Issue:27 Volume:41 Page:5410-5419
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lavergne Olivier¹,Lesueur-Ginot Laurence¹,Pla Rodas Francesc¹,Kasprzyk Philip G.¹,Pommier Jacques¹,Demarquay Danièle¹,Prévost Grégoire¹,Ulibarri Gérard¹,Rolland Alain¹,Schiano-Liberatore Anne-Marie¹,Harnett Jeremiah¹,Pons Dominique¹,Camara José¹,Bigg Dennis C. H.¹

Affiliation:

1. Institut Henri Beaufour, 5, avenue du Canada, F-91966 Les Ulis, France, Laboratorios Lasa, carretera Laureà Miró, 395, E-08980 San Feliu de Llobregat, Spain, and Biomeasure Inc., 27 Maple Street, Milford, Massachusetts 01757-3650

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980400l

Reference49 articles.

1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

2. Burris, H. A.; Fields, S. M.; Kuhn, J. G.; Von Hoff, D. D. Camptothecins: Dose-Limiting Toxicities and Their Management. InCamptothecins: NewAnticancer Agents; Potmesil, M., Pinedo, H. M., Eds.; CRC Press: Boca Raton, FL, 1995; pp 113−121.

3. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

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