Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications-Reference-Cited by-同舟云学术

Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications

Published:2014-12-09 Issue:24 Volume:57 Page:10527-10543
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Maderna Andreas¹,Doroski Matthew¹,Subramanyam Chakrapani¹,Porte Alexander¹,Leverett Carolyn A.¹,Vetelino Beth C.¹,Chen Zecheng¹,Risley Hud¹,Parris Kevin¹,Pandit Jayvardhan¹,Varghese Alison H.¹,Shanker Suman¹,Song Cynthia¹,Sukuru Sai Chetan K.¹,Farley Kathleen A.¹,Wagenaar Melissa M.¹,Shapiro Michael J.¹,Musto Sylvia²,Lam My-Hanh²,Loganzo Frank²,O’Donnell Christopher J.¹

Affiliation:

1. Worldwide Medicinal Chemistry, Oncology, Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

2. Oncology Research Unit, Pfizer Worldwide Research and Development, 401 North Middletown Road, Pearl River, New York 10965, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501649k

Reference48 articles.

1. The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

2. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal