Design and synthesis of novel site-specific antibody-drug conjugates that target TROP2

Author:

Luo Caili,Ren AnniORCID,Jin Zixuan,Zhang Jianxin,Shi Wei,Zeng Yue,Liu Zhaojun,Lu Mengru,Hou Yajing,Tang FengORCID,Huang WeiORCID

Publisher

Elsevier BV

Reference37 articles.

1. Antibody–drug conjugates come of age in oncology;Dumontet;Nat Rev Drug Discov,2023

2. A review of the current FDA-approved antibody-drug conjugates: landmark clinical trials and indications;Kesireddy;Pharm Med,2023

3. Expression of Trop2 cell surface glycoprotein in normal and tumor tissues: potential implications as a cancer therapeutic target;Stepan;J Histochem Cytochem,2011

4. Trop2 is a potential biomarker for the promotion of EMT in human breast cancer;Zhao;Oncol Rep,2018

5. Trop2 binding IGF2R induces gefitinib resistance in NSCLC by remodeling the tumor microenvironment;Sun;J Cancer,2021

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