1. Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada
2. Program in Molecular Medicine, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
3. Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada
4. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada
5. Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada