Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments-Reference-Cited by-同舟云学术

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

Published:2020-02-14 Issue:10 Volume:142 Page:4904-4915
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Guéret Stéphanie M.¹²^ORCID,Thavam Sasikala³,Carbajo Rodrigo J.⁴,Potowski Marco³⁵,Larsson Niklas⁶,Dahl Göran⁷,Dellsén Anita⁸,Grossmann Tom N.⁹^ORCID,Plowright Alleyn T.²,Valeur Eric²^ORCID,Lemurell Malin²^ORCID,Waldmann Herbert³⁵^ORCID

Affiliation:

1. Department of Chemical Biology, AstraZeneca-Max Planck Institute Satellite Unit, Max-Planck-Institute of Molecular Physiology, 44227 Dortmund, Germany

2. Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden

3. Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, 44227 Dortmund, Germany

4. Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0SL, United Kingdom

5. Faculty of Chemistry and Chemical Biology, TU Dortmund University, 44227 Dortmund, Germany

6. Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden

7. Structure, Biophysics & Fragment Based Lead Generation, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden

8. Mechanistic Biology & Profiling, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden

9. Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

http://pubs.acs.org/doi/pdf/10.1021/jacs.0c00269

Reference70 articles.

1. Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality

2. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

3. New Modalities for Challenging Targets in Drug Discovery

4. Comprehensive analysis of loops at protein-protein interfaces for macrocycle design

5. Analysis of Loops that Mediate Protein–Protein Interactions and Translation into Submicromolar Inhibitors

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