Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells-Reference-Cited by-同舟云学术

Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells

Published:2020-03-16 Issue:14 Volume:142 Page:6477-6482
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Lee Miseon¹,Maji Basudeb¹²,Manna Debasish¹²^ORCID,Kahraman Sevim³⁴^ORCID,Elgamal Ruth M.¹²,Small Jonnell¹⁵,Kokkonda Praveen¹,Vetere Amedeo¹,Goldberg Jacob M.⁶^ORCID,Lippard Stephen J.⁶^ORCID,Kulkarni Rohit N.³⁴,Wagner Bridget K.¹^ORCID,Choudhary Amit¹²⁵^ORCID

Affiliation:

1. Chemical Biology and Therapeutics Science, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States

2. Divisions of Renal Medicine and Engineering, Brigham and Women’s Hospital, Boston, Massachusetts 02115, United States

3. Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts 02215, United States

4. Harvard Stem Cell InstituteHarvard Medical School, Cambridge, Massachusetts 02138, United States

5. Chemical Biology Program, Harvard University, Cambridge, Massachusetts 02138, United States

6. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Burroughs Wellcome Fund

Integrated Islet Distribution Program

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

http://pubs.acs.org/doi/pdf/10.1021/jacs.0c00099

Reference37 articles.

1. β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

2. The Stunned β Cell: A Brief History

3. Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα

4. Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening

5. Chemical Methods to Induce Beta-Cell Proliferation

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