Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet-Reference-Cited by-同舟云学术

Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet

Published:2011-08-26 Issue:18 Volume:54 Page:6295-6304
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Okamoto Mayumi¹²,Irii Hiroyuki¹,Tahara Yu³,Ishii Hiroyuki⁴,Hirao Akiko³,Udagawa Haruhide²,Hiramoto Masaki²,Yasuda Kazuki²,Takanishi Atsuo⁴,Shibata Shigenobu³,Shimizu Isao¹

Affiliation:

1. Department of Applied Chemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku-ku, Tokyo, Japan

2. Department of Metabolic Disorder, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan

3. Department of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Shinjuku-ku, Tokyo, Japan

4. Faculty of Science and Engineering, Waseda University, Shinjuku-ku, Tokyo, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200662c

Reference39 articles.

1. Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition

2. Modulation of Fatty Acid Metabolism as a Potential Approach to the Treatment of Obesity and the Metabolic Syndrome

3. Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets