Construction of Multifunctional Modules for Drug Discovery: Synthesis of Novel Thia/Oxa-Azaspiro[3.4]octanes
Author:
Affiliation:
1. Laboratorium für Organische Chemie, ETH Zürich, CH-8093 Zürich, Switzerland, and Discovery Research, Chemistry Technologies & Innovation, F. Hoffmann-La Roche AG, CH-4070 Basel, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol402127b
Reference21 articles.
1. Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
2. Expanding the Azaspiro[3.3]heptane Family: Synthesis of Novel Highly Functionalized Building Blocks
3. Synthesis of Novel Azaspiro[3.4]octanes as Multifunctional Modules in Drug Discovery
4. The synthesis of 3-aryl-3-azetidinyl acetic acid esters by rhodium(I)-catalysed conjugate addition of organoboron reagents
5. Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry
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