Uncommon Arrangement of Self-resistance Allows Biosynthesis of de novo Purine Biosynthesis Inhibitor that Acts as an Immunosuppressor-Reference-Cited by-同舟云学术

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Uncommon Arrangement of Self-resistance Allows Biosynthesis of de novo Purine Biosynthesis Inhibitor that Acts as an Immunosuppressor

Published:2023-12-05 Issue:49 Volume:145 Page:26883-26889
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Sato Michio¹,Sakano Sakurako¹,Nakahara Miku¹,Tamura Yui¹,Hara Kodai¹,Hashimoto Hiroshi¹,Tang Yi^ORCID,Watanabe Kenji¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan

Funder

Japan Society for the Promotion of Science

Secom Science and Technology Foundation

Uehara Memorial Foundation

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c09600

Reference22 articles.

1. FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231. Taxonomy of the Producing Organism, Fermentation, Isolation,Physico-chemical Properties and Biological Activities.

2. Pharmacology of calcineurin antagonists

3. Biosynthesis of the Immunosuppressant (−)-FR901483

4. The DrrC protein ofStreptomyces peucetius, a UvrA-like protein, is a DNA-binding protein whose gene is induced by daunorubicin

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