Biosynthesis of the Immunosuppressant (−)-FR901483-Reference-Cited by-同舟云学术

Biosynthesis of the Immunosuppressant (−)-FR901483

Published:2020-12-29 Issue:1 Volume:143 Page:132-136
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhang Zhuan,Tamura Yui¹,Tang Mancheng,Qiao Tianzhang,Sato Michio¹,Otsu Yoshihiro²,Sasamura Satoshi²,Taniguchi Masatoshi²,Watanabe Kenji¹^ORCID,Tang Yi^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422-8526, Japan

2. Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki 300-2611, Japan

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.0c12352

Reference35 articles.

1. FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231. Taxonomy of the Producing Organism, Fermentation, Isolation,Physico-chemical Properties and Biological Activities.

2. FR901483: Synthetic Efficiency Remains a Challenge

3. Total Synthesis of (−)-FR901483

4. An Enantiospecific Synthesis of the Potent Immunosuppressant FR901483

5. Synthesis of the azatricyclic core of FR901483 by bridgehead vinylation via an anti-Bredt iminium ion

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