A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment-Reference-Cited by-同舟云学术

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A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment

Published:2011-03-28 Issue:8 Volume:54 Page:2714-2726
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cai Qian¹,Sun Haiying¹,Peng Yuefeng¹,Lu Jianfeng¹,Nikolovska-Coleska Zaneta¹,McEachern Donna¹,Liu Liu¹,Qiu Su¹,Yang Chao-Yie¹,Miller Rebecca¹,Yi Han¹,Zhang Tao²,Sun Duxin²,Kang Sanmao³,Guo Ming³,Leopold Lance³,Yang Dajun³,Wang Shaomeng¹

Affiliation:

1. Comprehensive Cancer Center and Departments of Internal Medicine, Pharmacology, and Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States

2. Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States

3. Ascenta Therapeutics, 101 Lindenwood Drive, Malvern, Pennsylvania 19355, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101505d

Reference50 articles.

1. From bench to clinic with apoptosis-based therapeutic agents

2. Cancer genetics

3. Apoptosis in cancer

4. The Hallmarks of Cancer

5. IAP proteins: blocking the road to death's door

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