Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity-Reference-Cited by-同舟云学术

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Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity

Published:2024-04 Issue: Volume:224 Page:35-46
ISSN:1046-2023
Container-title:Methods
language:en
Short-container-title:Methods

Author:

Huang Qingsheng^ORCID,Peng Yin,Peng Yuefeng,Lin Huijuan,Deng Shiqi,Feng Shengzhong,Wei Yanjie

Funder

Ministry of Science and Technology of the People's Republic of China

People's Government of Guangdong Province

Hanshan Normal University

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Elsevier BV

Reference44 articles.

1. XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs;Scott;EMBO J.,2005

2. X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy;Obexer;Front. Oncol.,2014

3. The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give Lead compounds with in vivo antitumor activity;Seigal;J. Med. Chem.,2015

4. SMAC mimetics induce autophagy-dependent apoptosis of HIV-1-infected macrophages;Campbell;Cell Death Dis.,2020

5. Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic;Miles;Apoptosis : an International Journal on Programmed Cell Death,2020

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1. Artificial intelligence and Computer-Aided Drug Discovery: Methods Development and Application;Methods;2024-09

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