New Trisubstituted 1,2,4-Triazole Derivatives as Potent Ghrelin Receptor Antagonists. 3. Synthesis and Pharmacological in Vitro and in Vivo Evaluations-Reference-Cited by-同舟云学术

New Trisubstituted 1,2,4-Triazole Derivatives as Potent Ghrelin Receptor Antagonists. 3. Synthesis and Pharmacological in Vitro and in Vivo Evaluations

Published:2008-01-15 Issue:3 Volume:51 Page:689-693
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Moulin Aline¹,Demange Luc¹,Ryan Joanne¹,Mousseaux Delphine¹,Sanchez Pierre¹,Bergé Gilbert¹,Gagne Didier¹,Perrissoud Daniel¹,Locatelli Vittorio¹,Torsello Antonio¹,Galleyrand Jean-Claude¹,Fehrentz Jean-Alain¹,Martinez Jean¹

Affiliation:

1. Institut des Biomolécules Max Mousseron, UMR 5247, CNRS, Universités Montpellier 1, Montpellier 2, BP 14491, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France, Zentaris GmbH, Weismuellerstrasse 50, 60314 Frankfurt am Main, Germany, and Department of Experimental Medicine, School of Medicine, University of Milano-Bicocca, Via Cadore 48, 20052 Monza (MI), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701292s

Reference17 articles.

1. Ghrelin is a growth-hormone-releasing acylated peptide from stomach

2. A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

3. Ghrelin: Structure and Function

4. Biological, Physiological, Pathophysiological, and Pharmacological Aspects of Ghrelin

5. A role for ghrelin in the central regulation of feeding

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