Role of the Hydrogen Bonding Heteroatom−Lys53 Interaction between the p38α Mitogen-Activated Protein (MAP) Kinase and Pyridinyl-Substituted 5-Membered Heterocyclic Ring Inhibitors-Reference-Cited by-同舟云学术

Role of the Hydrogen Bonding Heteroatom−Lys53 Interaction between the p38α Mitogen-Activated Protein (MAP) Kinase and Pyridinyl-Substituted 5-Membered Heterocyclic Ring Inhibitors

Published:2009-03-20 Issue:8 Volume:52 Page:2613-2617
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Thaher Bassam Abu¹,Koch Pierre¹,Schattel Verena¹,Laufer Stefan¹

Affiliation:

1. Faculty of Science, Chemistry Department, Islamic University of Gaza, Gaza Strip, Palestine, and Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Eberhard-Karls-University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801467h

Reference22 articles.

1. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

2. p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials

3. MAP Kinase p38Inhibitors: Clinical Results and an Intimate Look at Their Interactions with p38α Protein

4. Structural basis of inhibitor selectivity in MAP kinases

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