Synthesis of a Bicyclic Piperazine froml-Aspartic Acid and Application of a Fluoride-Promoted SNAr Coupling-Reference-Cited by-同舟云学术

Synthesis of a Bicyclic Piperazine froml-Aspartic Acid and Application of a Fluoride-Promoted SNAr Coupling

Published:2011-09-16 Issue:6 Volume:15 Page:1328-1335
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Sieser Janice E.¹,Singer Robert A.¹,McKinley Jason D.¹,Bourassa Dennis E.¹,Teixeira John J.¹,Long James²

Affiliation:

1. Chemical Research and Development, Pfizer Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, United States

2. Chemical Research and Development, Pfizer Worldwide Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent CT13 9NJ, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op2001854

Reference39 articles.

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2. Novel Bicyclic Piperazine Derivatives of Triazolotriazine and Triazolopyrimidines as Highly Potent and Selective Adenosine A2A Receptor Antagonists

3. Synthesis, sar and pharmacology of CP-293,019: A potent, selective dopamine D4 receptor antagonist

4. Bright, G. M.; Desai, K. A.U.S. Patent 5,122,525, 1992;

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