Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling-Reference-Cited by-同舟云学术

Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling

Published:2016-06-09 Issue:7 Volume:20 Page:1191-1202
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Duan Shengquan¹,Place David¹,Perfect Hahdi H.¹,Ide Nathan D.¹,Maloney Mark¹,Sutherland Karen¹,Price Wiglesworth Kristin E.¹,Wang Ke¹,Olivier Mark¹,Kong Fangming¹,Leeman Kyle¹,Blunt Jon²,Draper John²,McAuliffe Marie³,O’Sullivan Maria³,Lynch Denis³

Affiliation:

1. Chemical Research and Development and Analytical Research and Development, Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States

2. Chemical Research and Development, Pfizer Process Development Facility, Ramsgate Road, Sandwich, Kent, CT13 9NJ, United Kingdom

3. Pfizer Global Supply, Ringaskiddy, Co. Cork, Ireland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00070

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